Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Home Print this page Email this page Small font size Default font size Increase font size Users Online: 158
ARTICLE
Year : 2011  |  Volume : 34  |  Issue : 3  |  Page : 206-209

A study of Helicobacter pylori infection using the 14 C UBT method


1 Centre for Application of Radioisotopes and Radiation Technology, Mangalore University, Mangalagangotri, Karnataka, India
2 Radioanalytical laboratory, Board of Radiation and Isotope Technology, Navi Mumbai, Maharashtra, India
3 Department of Physiology K S Hegde Medical Academy, NITTE University, Deralakatte, Mangalore, Karnataka, India

Correspondence Address:
K Swaroop
Centre for Application of Radioisotopes and Radiation Technology, Mangalore University, Mangalagangotri, Karnataka
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-0464.101726

Rights and Permissions

Carbon-14 ( 14 C) is present in the environment and in all organic materials and behaves in the environment in the same manner as other carbon isotopes. In medicine, 14 C can be injected to study abnormalities of metabolism that underlie diabetes, gout, anaemia and acromegaly (adult "gigantism"), and for diagnosis of Helicobacter pylori (H. pylori). The discovery H. pylori by Warren and Marshall in 1982 changed the approach to treat peptic ulcer disease (PUD). Since then H. pylori has been the focus of clinical research and debate. The causal relationship between H. pylori infection and chronic gastritis is well established. H. pylori infection is one of the most common human infections worldwide. This organism has been shown to infect over half of the world's population. This article presents the application of 14 C Urea Breath Test ( 14 C UBT) for the diagnosis of the H. pylori bacteria which present in the stomach and duodenum. 14 C UBT relies on the urease activity of H. pylori to detect the presence of active infection. 14 C UBT has proved to be one of the most accurate methods for assessing H. pylori status. The ionizing radiation dose involved in this test is extremely low, much lower than the radiation dose due to natural sources. 209 samples collected from both symptomatic and non-symptomatic persons of Dakhina Kannada District, Karnataka were analysed and the results with discussion are presented in this paper.


[FULL TEXT] [PDF]*
Print this article     Email this article
Next article
Previous article
Table of Contents
Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
Citation Manager
Access Statistics
Reader Comments
Email Alert *
Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1709    
    Printed55    
    Emailed3    
    PDF Downloaded194    
    Comments [Add]    

Recommend this journal