ARTICLE |
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Year : 2010 | Volume
: 33
| Issue : 4 | Page : 199-201 |
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Effect of tumour promoter iodoacetate on γ-radiation induced chromosomal aberrations in human lymphocytes
KB Anjaria, KB Shirsath, NN Bhat, B Sreedevi
Radiological Physics and Advisory Division, Bhabha Atomic Research Centre, Trombay, Mumbai, India
Correspondence Address:
K B Anjaria Radiological Physics and Advisory Division, Bhabha Atomic Research Centre, Trombay, Mumbai India
 Source of Support: None, Conflict of Interest: None  | Check |

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Iodoacetate (IA) is a known tumour promoter of moderate potency. Present study reports the effect of IA post-treatment on 60 Co gamma radiation induced chromosomal aberrations in human peripheral blood lymphocytes. Cells were exposed to 2 or 4 Gy of radiation and were cultured in the presence of 0.25-2.5 μg/ml IA. It was observed that IA reduced radiation induced dicentrics yield significantly at both the radiation doses. |
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