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Year : 2021  |  Volume : 44  |  Issue : 1  |  Page : 22-27

Dosimetric comparison of coplanar intensity-modulated radiotherapy, noncoplanar intensity-modulated radiotherapy, and volumetric arc therapy planning technique in hippocampal-sparing whole-brain radiotherapy

Department of Radiation Oncology, Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute, Mumbai, Maharashtra, India

Correspondence Address:
Ajay Vindhyachal Sharma
Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute, Mumbai, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/rpe.rpe_48_20

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The aim of this study was to compare the dosimetric parameters of Co-planar Intensity modulated radiotherapy (C-IMRT), non-coplanar (NC-IMRT), and volumetric arc therapy (VMAT) planning technique in hippocampal sparing (HS) whole brain radiotherapy (WBRT). Fifteen patients of brain metastasis (BM) treated with hippocampal sparing whole-brain palliative radiation were selected for this study. C-IMRT, NC-IMRT and VMAT plans were generated for the comparison. Generated plans were evaluated based on planning target volume (PTV) coverage, conformity index (CI), homogeneity index (HI), beam-on time (BOT) and dose delivered to organs at risk (OARs) for the prescribed dose (PD) of 30 Gy in 10 fractions. Statistically significant difference was found in PTVD95%, PTVmax, HI, BOT, MU, Dmax of the brainstem, Dmean of eyes, Dmax of lenses and Dmax, Dmean and D2% of the bilateral hippocampus. However, a non-significant difference was observed in CI, D100% of both the hippocampus, Dmax of the optic chiasm, optic nerves, and Dmax of eyes in all the three planning techniques. Considering the superior plan quality, both NC-IMRT and VMAT are better than the C-IMRT planning technique. Based on beam-on time and delivery efficiency VMAT is found to be superior to both the C-IMRT and NC-IMRT technique. Doses to OARs are very well within the limits in all the three planning techniques.

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